A booster shot of the anti-COVID-19 vaccine developed by Pfizer/BioNTech is 95.6 per cent effective against symptomatic infection, according to trial data published by the makers on Thursday.
The clinical phase three trial with “10,000 participants 16 years of age and older” showed “a relative vaccine efficacy of 95.6 per cent against disease during a period when Delta was the prevalent strain”, the companies said in a statement.
The study presented the “first results” of a booster trial, with a third shot of the vaccine demonstrating a “favourable safety profile”.
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“These results provide further evidence of the benefits of boosters as we aim to keep people well-protected against this disease,” said Pfizer CEO Albert Bourla.
The preliminary results would be shared with regulatory agencies “as soon as possible”, the companies said in the statement.
Several countries have already approved COVID-19 booster shots to increase immunity in people who have already been vaccinated, but whose protection may have dipped after several months, per some studies.
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In the United States, the federal Food and Drug Administration (FDA) approved a third dose in September for everyone aged 65 and up, as well as people at high risk of developing severe COVID.
The European Medicines Agency (EMA) approved a booster for over-18s at the beginning of October, allowing national regulators to decide which groups should be eligible first.
In Israel, authorities have gone further, approving booster shots for everyone aged 12 and over.